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MRS 2481
CAS No. 859724-30-4
MRS 2481( MRS2481 )
Catalog No. M16230 CAS No. 859724-30-4
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMRS 2481
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NoteResearch use only, not for human use.
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Brief DescriptionMRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM.
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DescriptionMRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity; also is a potent inhibitor of TNFα-induced phosphorylation and proteosomal destruction of IκBα, inhibits both NFκB and AP-1 signaling on the IL-8 promoter (IC50=1.8 uM); blocks TNFα-activated phosphorylation of JNK, the c-JUN kinase.
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In Vitro——
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In Vivo——
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SynonymsMRS2481
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PathwayOthers
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TargetAmyloids
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RecptorAmyloids
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Research Area——
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Indication——
Chemical Information
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CAS Number859724-30-4
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Formula Weight420.391
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Molecular FormulaC22H30BrNO2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(R)-1-(8-((2-phenylpropanoyl)oxy)octyl)pyridin-1-ium bromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Diaz JC, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3348-53.
2. Tchilibon S, et al. Biochem Pharmacol. 2005 Aug 1;70(3):381-93.
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